The goal of the Marathon of Hope Cancer Centre Network (MOHCCN) is to accelerate the adoption of Precision Medicine for cancer patients through the creation of a pan-Canadian Network of designated Cancer Centres. The Network supports the unification of top-tier cancer researchers and clinicians and the sharing of data, the development and validation of exciting new technologies and the delivery of the best outcomes for every cancer patient in Canada, no matter where they live.
Supported by MOHCCN Committees and Working Groups, the development of MOHCCN policies and guidelines are key components required for the development and responsible sharing of Network data.
Key to the success of the Network are the shared values, principles and practices of the Marathon of Hope Research Community that are embedded in the MOHCCN Researcher Code of Conduct and apply both to individual community members and their host institutions. These shared values, principles and practices guide the expectations of those that are using MOHCCN data to further the adoption of precision medicine in Canada.
The Marathon of Hope Cancer Centres Network (MOHCCN) Data Access and Use Policy defines the procedures and timelines for access to and use of data shared with the Network in research endeavors. The Policy aims to expedite data access to the Network. Network Data includes all data that is generated with the use of MOHCCN funding and made available by the Network and its Partners. Network Data may include genomic and other molecular data types, along with clinical and other health-related information.
The Marathon of Hope Cancer Centres Network (MOHCCN) aims to create a “Gold Cohort” of clinical cancer specimens with a well-annotated, uniformly generated, and consistently quality-controlled dataset (clinical and genomic) from 15,000 (15k) cases collected from across Canada over 5 years. The Technology Working Group (TWG) has developed the current policy to define the data requirements to complete a MOHCCN Gold Standard Case. This policy will be followed by additional guidelines to support the collection of data around each case.
The Data Standards Sub-Committee (DSC) has been set up as a sub-committee of the Data Policies and Standards Committee. The goal of the DSC is to support the harmonization of data across cohorts and the promotion of uniform analysis.
| Clinical Data Model v2.1 | Here you can download the second version of the MOHCCN Clinical Data Model. | |
| Clinical Data Model v2.1 Guidelines | Here you can download the guidelines for the MOHCCN Clinical Data Model 2.1. | |
| Clinical Data Model v2.1 Release Notes | Here you can see the changes between v2.1 and v2 of the MOHCCN Clinical Data Model. | |
| ER Diagram | Here you can download the ER Diagram for MOHCCN Clinical Data fields. |
The MOHCCN Publication Policy establishes a definition of a MOHCCN Network publication. It includes guidelines for authorship and acknowledgement components. The Policy contains an outline of the requirements for publications authored by members of the Network using Network data.
The Marathon of Hope Cancer Centres Network (MOHCCN) aims to create a “Gold Cohort” of clinical cancer specimens with a well-annotated, uniformly generated, and consistently quality-controlled dataset (clinical and genomic) from 15,000 (15k) cases collected from across Canada over 5 years. The Technology Working Group (TWG), with the support of experts at the genome centres part of the Network, has developed the current guideline to provide recommendations for the generation of the Whole Genome and Transcriptome Sequencing (WGTS) data to the “gold standard”.
The Marathon of Hope Cancer Centres Network (MOHCCN) Biospecimens Working Group aims to create guidelines that will support harmonization of processes across Network centres. Nucleic acid isolation from formalin fixed paraffin embedded (FFPE) tissue is comprised of a series of activities from the selection and preparation of tissue to the qualification of DNA and RNA ahead of library preparation. This guideline will advise on all the processes related to these activities.
The purpose of this policy is to define eligibility requirements and the process for individual to become members of the Marathon of Hope Cancer Centres Network.
Researchers are able to use the following form to submit questions about MOHCCN data standards and guidelines and to request a change to the MOHCCN clinical data model.